CRS 2011 - drug solubility of ethyl cellulose membrane coating micro pill control release

We studied the drug solubility for love show ™ (ETHOCEL ™) medicinal grade ethyl cellulose (EC) coating pellet the effects of drug release.Drug solubility decrease, drug release delay.In addition to the drug solubility, other factors such as drug affinity of membrane control or drugs of ionization degree also can affect the drug release rate.