AAPS 2010 - quality from design principle in propranolol hydrochloride (QbD) the application of the hydrophilic skeleton zyban

The purpose of this study is based on the principle of the QbD, study of hydroxypropyl methyl cellulose physical and chemical properties change of slow-release hydrophilic matrix in the powder liquidity, tablet physical properties and the influence of the in vitro drug release curve.